Apolipoprotein CIII and N-terminal prohormone b-type natriuretic peptide as independent predictors for cardiovascular disease in type 2 diabetes

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OBSERVATIONS B-Type Natriuretic Peptide in Type 2 Diabetes

C ardiac ventricles release B-type natriuretic peptide (BNP) in response to volume expansion and pressure overload; therefore, BNP concentration may be used as a biochemical marker of cardiac failure (1). BNP levels are high in diabetic subjects with left ventricular dysfunction (2). Because the diagnosis of cardiac failure may be an emergency (3), it is important to know whether the timing of ...

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Role of B‐Type Natriuretic Peptide and N‐Terminal Prohormone BNP as Predictors of Cardiovascular Morbidity and Mortality in Patients With a Recent Coronary Event and Type 2 Diabetes Mellitus

BACKGROUND Natriuretic peptides are recognized as important predictors of cardiovascular events in patients with heart failure, but less is known about their prognostic importance in patients with acute coronary syndrome. We sought to determine whether B-type natriuretic peptide (BNP) and N-terminal prohormone B-type natriuretic peptide (NT-proBNP) could enhance risk prediction of a broad range...

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Perioperative B-type Natriuretic Peptide/N-terminal pro-B-type Natriuretic PeptideNext Steps to Clinical Practice

Anesthesiology, V 123 • No 2 246 August 2015 T HE heart is not only a pumping organ but also an endocrine organ. B-type natriuretic peptide (BNP) is secreted primarily by cardiac ventricular myocytes in response to increased ventricular wall stress induced by volume expansion, pressure overload, or ischemia.1 BNP protein formation begins with intracellular translation into a large preprohormone...

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Plasma Amino-Terminal B-Type Natriuretic Peptide

Measured by Elecsys 2010 Assay in a Trial of Hormoneguided Treatment for Heart Failure, Richard W. Troughton, Christopher M. Frampton, Timothy G. Yandle, Eric A. Espiner, Gary Nicholls, and Mark Richards (Christchurch Cardioendocrine Research Group, Christchurch School of Medicine and Health Sciences, Christchurch, 8001 New Zealand; * address correspondence to this author at: Department of Medi...

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N-terminal pro-B-type natriuretic peptide is an independent predictor of cardiovascular morbidity and mortality in the general population.

AIMS Natriuretic peptides including N-terminal pro-B-type natriuretic peptide (NT-proBNP) are established biomarkers in heart failure. However, their prognostic value in the general population is less well established. The purpose of our study was to investigate the prognostic properties of NT-proBNP for death and cardiovascular (CV) events in the general population. METHODS AND RESULTS In th...

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ژورنال

عنوان ژورنال: Atherosclerosis

سال: 2018

ISSN: 0021-9150

DOI: 10.1016/j.atherosclerosis.2018.05.014